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General Principles of Pharmacology

presented by Barbara Gladson

Accreditation Check:

Physical and Occupational Therapy literature provides limited coverage of medications commonly seen in practice. Additionally, these sources of information provide only superficial coverage of pharmacologic principles and how these relate to therapeutic interventions for our patients. The aim of this series is to present the most common drug categories seen in practice and discuss their interaction with exercise, when applicable. The first course in this series introduces learners to the general principles of pharmacology. Students will also learn how to recognize adverse drug events and to use physical findings to determine toxicity.

Meet Your Instructor

  • Barbara Gladson, PT, OT, PhD

    Dr. Gladson has earned a BS from the University of Pennsylvania in Occupational Therapy, a MS degree in Physical Therapy from Columbia and a PhD in Pharmacology from the Rutgers Graduate School of Biomedical Sciences. She is the Associate Dean for Academic Affairs in the School of Health Professions, and the Director of the Rutgers BioPharma Educational Initiative, MS in Clinical Trial Sciences, which educates individuals seeking to enter the Pharmaceutical Industry. Dr. Gladson's areas of teaching include Medical Pathophysiology, Pharmacokinetics, Cultural Diversity in Clinical Trials and Pharmacology. She has developed several web-based courses and has recently completed a textbook in pharmacology. Dr. Gladson’s research interests include methodology to improve subject recruitment efforts in clinical trials as well as in educating the public on the value of participating in a drug trial.

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Chapters & Learning Objectives

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  1. Introduction

    1. Introduction

    The first chapter of this course provides an introduction to pharmacology. A variety of introductory topics are covered, including the average number of prescriptions filled by elderly individuals in the U.S., and the phases of drug development.

  2. Pharmacokinetics

    2. Pharmacokinetics

    Pharmacokinetics describes a drug’s concentration in various tissues of a body over time. In Chapter Two, Dr. Barbara Gladson reviews the phases of pharmacokinetics (PK), from absorption until elimination. Dr. Gladson also discusses PK and cardiac disease, PK and liver disease, and PK changes with aging.

  3. Pharmacokinetics and Exercise

    3. Pharmacokinetics and Exercise

    In Chapter Three, Dr. Barbara Gladson explains the interactions between exercise and pharmacokinetics. She discusses why many drug-exercise studies are flawed and dispels incorrect assumptions regarding pharmacokinetics and exercise.