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Tissue Injury: Mechanisms of Inflammation and Repair

presented by Andrew J. Opett

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Disclosure Statement:

Financial— Andrew Opett receives compensation from MedBridge for the production of this course. There are no other relevant financial relationships. Nonfinancial— No relevant nonfinancial relationship exists.

Satisfactory completion requirements: All disciplines must complete learning assessments to be awarded credit, no minimum score required unless otherwise specified within the course.

MedBridge is committed to accessibility for all of our subscribers. If you are in need of a disability-related accommodation, please contact [email protected]. We will process requests for reasonable accommodation and will provide reasonable accommodations where appropriate, in a prompt and efficient manner.

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Video Runtime: 32 Minutes; Learning Assessment Time: 39 Minutes

This course provides an overview of the inflammatory process and the process of tissue repair following injury. The three distinct phases of inflammation and tissue repair will be discussed. The major chemical mediators of inflammation and their effects will be covered. The inflammation and tissue healing process in specific musculoskeletal tissues, including bone, muscle, tendon, ligament, and cartilage, will be discussed.

Meet Your Instructor

Andrew J. Opett, PT, DPT, OCS

Andrew Opett received a bachelor of science degree in biology from the State University of New York at Geneseo in 1996; a bachelor of science degree in health sciences from Nazareth College of Rochester, New York, in 2000; and a master of science degree in physical therapy from Nazareth College of Rochester, New York, in…

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Chapters & Learning Objectives

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1. Injury and Inflammation

This chapter will cover the process of inflammation, which is a necessary stage in tissue healing and repair. The cardinal signs of inflammation and the mechanisms behind their occurrence will be explained.

2. Chemical Mediators of the Inflammatory Process

This chapter will investigate more closely the chemical substances that are involved with the inflammatory process. The derivations of these chemical mediators will be discussed in order to better understand their function and how they contribute to the overall healing process following tissue injury. The relationship between chemical mediators of inflammation and the mechanism of action of the anti-inflammatory medications, including NSAIDs and corticosteroids, will be discussed. The difference between acute and chronic inflammation will also be discussed.

3. Proliferation and Maturation Phases of Tissue Healing: Epithelial Tissues

This chapter will look more closely at the proliferation and maturation phases of wound healing and repair in epithelial tissues. The key events in each of these stages will be discussed.

4. Proliferation and Maturation Phases of Tissue Healing: Musculoskeletal Tissues

This chapter will look more closely at the proliferation and maturation phases of wound healing and tissue repair for musculoskeletal tissues, including bone, tendon, ligament, muscle, and cartilage. Healing potential and healing times for each of these connective and muscular tissues will be discussed.

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