Financial: Todd Davenport, Mark VanNess, and Staci Stevens receive compensation from MedBridge for this course. There is no financial interest beyond the production of this course.
Non-Financial: Todd Davenport, Mark VanNess, and Staci Stevens have no competing non-financial interests or relationships with regard to the content presented in this course.
Satisfactory completion requirements: All disciplines must complete learning assessments to be awarded credit, no minimum score required unless otherwise specified within the course.
Todd Davenport, PT, DPT, MPH, OCS
Todd serves as a tenured associate professor in the Department of Physical Therapy in the Thomas J. Long School of Pharmacy and Health Sciences at the University of the Pacific in Stockton, California, where he teaches in the Doctor of Physical Therapy (DPT) program. Todd is a graduate of the University of Southern California’s DPT…Read full bio
Staci Stevens, MA
Staci Stevens holds a bachelor's degree in Sports Medicine and a master's degree in Exercise Physiology from the University of the Pacific in Stockton, California. Ms. Stevens, in conjunction with Workwell Foundation’s research team, pioneered the use of two-day cardiopulmonary exercise testing (CPET) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) to document the hallmark clinical feature…Read full bio
Mark VanNess, PhD
J. Mark VanNess, PhD, is a cardiovascular biologist and Distinguished Professor in the department of Health and Exercise Science at the University of the Pacific. He studied biology, chemistry, and exercise science as an undergraduate student and exercise physiology for his master’s degree. He received his doctoral degree from the program in Neuroscience at Florida…Read full bio
1. What's in a Name and Why Does it Matter?
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is identified on the basis of case definition criteria. Over time, several sets of case definition criteria have been developed. The purpose of this section is to describe the epidemiological background of case definition criteria, present the common contemporary case definition criteria for ME/CFS for use in the clinic, and discuss the relative utility of contemporary case definition criteria to identify ME/CFS.
2. Objective Evidence of Post-Exertional Malaise and Exercise Impairment in ME/CFS
The provocation of symptoms and signs in ME/CFS in response to exertion suggests the presence of measurable physiological deficits in the post-exertional state. A 2-day maximal cardiopulmonary exercise test (CPET) paradigm was devised, which has revealed a whole host of cardiac, pulmonary, metabolic, and symptomatic differences between people with ME/CFS and sedentary people after an initial bout of exertion. The purposes of this chapter are to acquaint the learner with the 2-day maximal CPET paradigm and to describe the scientific research it has generated regarding the physiological basis of post-exertional malaise.